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Table 3 Pro/anti-inflammatory cytokines production and metabolic markers in triathletes

From: Impacts of different triathlon races on systemic cytokine profile and metabolic parameters in healthy individuals: a systematic review

Author, Year

Category Analysis

Cytokines

Other Metabolic Outcomes

Banfi, 2008

Top-level Triathlon Serum

↑ IL-8; MCP-1

↑ EGF; VEGF

Bassit, 2000

Olympic Triathlon PMBC

↑ IL-1; IL-2; TNF-α / ↓ INF-γ

Ë—

Huang, 2019

Sprint Triathlon Serum

↑ IL-4; IL-6; IL-8; IL-10; INF-γ; TNF-α

= CK; ↑ FFA; LDH; Lactate; Myostatin

Jenkendrup, 2008

Ironman Triathlon Serum

= TNF-α; IL-6

↑ CRP

Merino, 2006

Long-distance Triathlon Serum

↑ IL-1ra; IL-6; IL-10; ↓ IL-8

↑ CK; FFA; = CRP

Neubauer, 2008

Ironman Triathlon Serum

↑ IL-6; IL-10

↑ CK; CRP; Cortisol; Myostatin

Nieman, 2004

World Championship Serum

↑IL-6; IL-8; IL-1ra; IL-10

↑ Cortisol

Pinho, 2010

Ironman Triathlon Serum/Plasma

↑ IL-1ra; IL-6; IL-10; TNF-α

↑ CK

Smith, 2019

Ultraman Triathlon Plasma

= IL-6; IL-17; IL-23; IL-10

↑ CRP

Suzuki, 2006

Ironman Triathlon Plasma

↑ IL-1ra; IL-6; IL-10; IL-12p40; = IL-1β; IL-4

↑ CK; FFA; LDH

  1. Caption: CK: Creatine Kinase; CRP: C-Reactive Protein; EGF: Endothelial Growth Factor; FFA: Free Fatty Acids; IL-1: Interleukin-1; IL-1β: Interleukin-1 Beta, IL-1ra: Interleukin-1 receptor agonist; IL-2: Interleukin-2; IL-4: Interleukin-4; IL-6: Interleukin-6; IL-8: Interleukin-8; IL-10: Interleukin-10; IL-17: Interleukin-17; IL-23: Interleukin-23; IFN-γ: Interferon-gamma; LDH: Lactate dehydrogenase; MCP-1: Monocyte Chemoattractant Protein-1;PMBC: Peripheral Mononuclear Blood Cells; TNF-α: Tumor Necrosis Factor-alpha; VEGF: Vascular Endothelial Growth Factor