Effectiveness of an 11-week exercise intervention for patients with hip or knee osteoarthritis: results of a quasi-experimental pragmatic trial

Table 5 Primary and secondary outcomes at t3, t6, t12 and t24 months change from baseline (cfb, 95% CI) in the intention-to-treat population

	Control (CO) n = 515	Hip Knee Training (HKT) n = 515	Estimated treatment difference CO—HKT	p-value	Effect Size
Secondary Outcomes (cont.)
Health-oriented activity status (Ho-AS)
Ho-AS t3	0.15 (0.03; 0.27)	-0.10 (-0.22; 0.03)	0.25 (0.13;0.37)	< 0.001	0.27
Ho-AS t6	0.18 (0.06; 0.31)	-0.04 (-0.17; 0.09)	0.23 (0.10; 0.35)	< 0.001	0.25
Ho-AS t12	0.19 (0.07; 0.31)	-0.03 (-0.16; 0.09)	0.22 (0.10; 0.35)	< 0.001	0.24
Ho-AS t24	0.23 (0.11; 0.36)	-0.05 (-0.17; 0.08)	0.28 (0.15; 0.41)	< 0.001	0.31

Linear Mixed Models (Time, Treatment, Time*Treatment, PS Propensity Score), Health-oriented activity status (Ho-AS, 1-5, best to worst). Scales best to worst (Ho-AS): positive estimated treatment difference indicate benefit for HKT. P-values for time*treatment interaction of the LMMs. For secondary outcomes alpha = 0.05 without claiming confirmatory interpretation of p-values. Positive effect sizes indicate benefit for HKT versus CO

ISSN: 2052-1847