Physical rehabilitation in the form of voluntary wheel running improves in vivo tibialis anterior muscle torque. Maximal isometric torque (@ 150 Hz) of the tibialis anterior muscle was assessed in vivo following distal extensor digitorum longus muscle (EDL) tenotomy (see Methods). Average maximal isometric torque normalized to body weight is shown for the uninjured and injured muscle for the SED and RUN groups. Values are mean ± SEM. Sample size is listed in Table 3. * ≠ uninjured (contralateral); § ≠ sedentary injured; p < 0.05. All VML responses, regardless of group, were lesser than uninjured contralateral values.