Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

Inoue, Takayuki; Ito, Satoru; Ando, Masahiko; Nagaya, Motoki; Aso, Hiromichi; Mizuno, Yota; Hattori, Keiko; Nakajima, Hiroki; Nishida, Yoshihiro; Niwa, Yukiko; Kodera, Yasuhiro; Koike, Masahiko; Hasegawa, Yoshinori

doi:10.1186/s13102-016-0060-y

BMC Sports Science, Medicine and Rehabilitation

Table 2 Correlation between preoperative parameters

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

Parameters		6MWD	Hand grip strength		Isometric knee extensor muscle strength
Parameters		6MWD	Right	Left	Right	Left
6MWD	r	1	0.562	0.511	0.482	0.535
6MWD	P value	0	0.001 (n = 34)	0.002 (n = 34)	0.006 (n = 31)	0.002 (n = 31)
CAT scores	r	−0.332	−0.490	−0.406	−0.491	−0.565
CAT scores	P value	0.068 (n = 31)	0.005 (n = 31)	0.024 (n = 31)	0.008 (n = 28)	0.002 (n = 28)
SF-36 component
Physical functioning	r	0.454	0.137	0.258	0.350	0.365
Physical functioning	P value	0.013 (n = 29)	0.478 (n = 29)	0.177 (n = 29)	0.080 (n = 26)	0.067 (n = 26)
Role physical	r	0.334	0.413	0.490	0.589	0.473
Role physical	P value	0.076 (n = 29)	0.026 (n = 29)	0.007 (n = 29)	0.002 (n = 26)	0.015 (n = 26)
Bodily pain	r	0.126	0.123	0.166	0.172	0.125
Bodily pain	P value	0.516 (n = 29)	0.525 (n = 29)	0.389 (n = 29)	0.401 (n = 26)	0.542 (n = 26)
General health	r	0.465	0.382	0.367	0.478	0.376
General health	P value	0.011 (n = 29)	0.041 (n = 29)	0.050 (n = 29)	0.014 (n = 26)	0.058 (n = 26)
Social functioning	r	0.334	0.221	0.221	0.370	0.306
Social functioning	P value	0.077 (n = 29)	0.249 (n = 29)	0.248 (n = 29)	0.063 (n = 26)	0.128 (n = 26)
Vitality	r	0.287	0.356	0.398	0.433	0.283
Vitality	P value	0.131 (n = 29)	0.058 (n = 29)	0.034 (n = 29)	0.027 (n = 26)	0.161 (n = 26)
Role emotional	r	0.243	0.197	0.317	0.515	0.385
Role emotional	P value	0.204 (n = 29)	0.305 (n = 29)	0.093 (n = 29)	0.007 (n = 26)	0.052 (n = 26)
Mental health	r	0.382	0.124	0.317	0.355	0.310
Mental health	P value	0.045 (n = 28)	0.529 (n = 28)	0.093 (n = 28)	0.081 (n = 25)	0.131 (n = 25)
PCS	r	0.159	0.345	0.346	0.284	0.228
PCS	P value	0.436 (n = 26)	0.084 (n = 26)	0.083 (n = 26)	0.189 (n = 23)	0.296 (n = 23)
MCS	r	0.497	0.220	0.180	0.354	0.349
MCS	P value	0.010 (n = 26)	0.281 (n = 26)	0.379 (n = 26)	0.097 (n = 23)	0.103 (n = 23)
RCS	r	0.292	0.225	0.345	0.587	0.435
RCS	P value	0.148 (n = 26)	0.269 (n = 26)	0.084 (n = 26)	0.003 (n = 23)	0.038 (n = 23)

Spearman’s rank correlation coefficient was used for the analysis. 6MWD 6-min walk distance, CAT COPD assessment test, SF-36 the MOS 36-item Short-Form Health Survey Questionnaire, PCS physical component summary, MCS mental component summary, RCS, role/social component summary

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