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Table 7 Comparison of data with and without COPD

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

  Non-COPD (n = 22) COPD (n = 12) P value
Pre %FEV1 101.3 ± 12.7 75.2 ± 21.1 <0.001*
Pre FEV1/FVC, % 77.3 ± 5.7 60.5 ± 16.3 <0.001*
Pre 6MWD, m 509 ± 80 466 ± 60 0.127
Desaturation during 6MWTa N = 3 N = 2 0.580
Post 6MWD, m 438 ± 100 (n = 21) 351 ± 105 (n = 11) 0.034*
Desaturation during 6MWTa N = 2 N = 3 0.290
Changes in 6MWD, m −70 ± 83 (n = 21) −114 ± 98 (n = 11) 0.123
Pre hand grip strength, kgf
 Right 32.4 ± 8.4 28.4 ± 10.5 0.204
 Left 30.7 ± 8.8 27.0 ± 9.4 0.204
Post hand grip strength, kgf
 Right 29.6 ± 7.9 (n = 21) 26.6 ± 9.7 0.152
 Left 28.7 ± 7.3 (n = 21) 25.8 ± 8.0 0.242
Pre isometric knee extensor muscle strength, kgf
 Right 26.7 ± 8.2 (n = 20) 24.7 ± 9.4 (n = 11) 0.502
 Left 27.6 ± 8.9 (n = 20) 20.1 ± 9.1 (n = 11) 0.018*
Post isometric knee extensor muscle strength, kgf
 Right 25.8 ± 8.3 (n = 20) 22.8 ± 8.0 (n = 11) 0.183
 Left 24.9 ± 7.7 (n = 20) 19.3 ± 6.9 (n = 11) 0.020*
 Pre HADS anxiety 6.1 ± 2.8 (n = 21) 4.5 ± 3.2 (n = 10) 0.135
  Scores ≥ 8 N = 5 N = 2 1
 Pre HADS depression 5.6 ± 3.2 (n = 21) 5.5 ± 4.1 (n = 10) 0.852
  Scores ≥ 8 N = 5 N = 4 0.781
 Post HADS anxiety 4.8 ± 3.3 (n = 15) 5.6 ± 5.4 (n = 8) 0.925
  Scores ≥ 8 N = 4 N = 4 0.676
 Post HADS depression 5.7 ± 3.8 (n = 15) 4.9 ± 4.1 (n = 8) 0.681
  Scores ≥ 8 N = 5 N = 2 1
 Pre CAT (n = 31) 8.1 ± 5.5 (n = 21) 14.2 ± 5.5 (n = 10) 0.008*
 Post CAT (n = 24) 14.1 ± 5.3 (n = 16) 19.6 ± 9.6 (n = 8) 0.136
Pre SF-36 component
 Physical functioning 49.5 ± 15.1 (n = 19) 40.9 ± 15.5 (n = 10) 0.308
 Role physical 37.6 ± 19.3 (n = 19) 38.1 ± 21.6 (n = 10) 0.456
 Bodily pain 44.8 ± 12.9 (n = 19) 41.4 ± 24.5 (n = 10) 0.804
 General health 45.3 ± 9.5 (n = 19) 45.4 ± 11.4 (n = 10) 0.946
 Vitality 43.2 ± 17.6 (n = 19) 39.0 ± 18.4 (n = 10) 0.804
 Social functioning 49.0 ± 11.2 (n = 19) 38.8 ± 17.3 (n = 10) 0.069
 Role emotional 41.3 ± 18.2 (n = 19) 40.7 ± 17.0 (n = 10) 0.604
 Mental health 49.3 ± 14.3 (n = 19) 38.4 ± 12.7 (n = 9) 0.061
 PCS 46.7 ± 5.8 (n = 19) 52.5 ± 9.7 (n = 7) 0.209
 MCS 51.2 ± 10.1 (n = 19) 45.5 ± 9.6 (n = 7) 0.073
 RCS 38.1 ± 12.4 (n = 19) 36.3 ± 23.3 (n = 7) 0.955
  1. Values are mean ± SD and compared by paired t-test, Mann-Whitney U test or Fisher’s exact test. *P < 0.05. aDesaturation was defined as a fall in SpO2 ≥ 4 % or SpO2 < 90 %. The HADS score ≥8 denotes a probable case. Pre preoperative, Post postoperative