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Table 7 Comparison of data with and without COPD

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

 

Non-COPD (n = 22)

COPD (n = 12)

P value

Pre %FEV1

101.3 ± 12.7

75.2 ± 21.1

<0.001*

Pre FEV1/FVC, %

77.3 ± 5.7

60.5 ± 16.3

<0.001*

Pre 6MWD, m

509 ± 80

466 ± 60

0.127

Desaturation during 6MWTa

N = 3

N = 2

0.580

Post 6MWD, m

438 ± 100 (n = 21)

351 ± 105 (n = 11)

0.034*

Desaturation during 6MWTa

N = 2

N = 3

0.290

Changes in 6MWD, m

−70 ± 83 (n = 21)

−114 ± 98 (n = 11)

0.123

Pre hand grip strength, kgf

 Right

32.4 ± 8.4

28.4 ± 10.5

0.204

 Left

30.7 ± 8.8

27.0 ± 9.4

0.204

Post hand grip strength, kgf

 Right

29.6 ± 7.9 (n = 21)

26.6 ± 9.7

0.152

 Left

28.7 ± 7.3 (n = 21)

25.8 ± 8.0

0.242

Pre isometric knee extensor muscle strength, kgf

 Right

26.7 ± 8.2 (n = 20)

24.7 ± 9.4 (n = 11)

0.502

 Left

27.6 ± 8.9 (n = 20)

20.1 ± 9.1 (n = 11)

0.018*

Post isometric knee extensor muscle strength, kgf

 Right

25.8 ± 8.3 (n = 20)

22.8 ± 8.0 (n = 11)

0.183

 Left

24.9 ± 7.7 (n = 20)

19.3 ± 6.9 (n = 11)

0.020*

 Pre HADS anxiety

6.1 ± 2.8 (n = 21)

4.5 ± 3.2 (n = 10)

0.135

  Scores ≥ 8

N = 5

N = 2

1

 Pre HADS depression

5.6 ± 3.2 (n = 21)

5.5 ± 4.1 (n = 10)

0.852

  Scores ≥ 8

N = 5

N = 4

0.781

 Post HADS anxiety

4.8 ± 3.3 (n = 15)

5.6 ± 5.4 (n = 8)

0.925

  Scores ≥ 8

N = 4

N = 4

0.676

 Post HADS depression

5.7 ± 3.8 (n = 15)

4.9 ± 4.1 (n = 8)

0.681

  Scores ≥ 8

N = 5

N = 2

1

 Pre CAT (n = 31)

8.1 ± 5.5 (n = 21)

14.2 ± 5.5 (n = 10)

0.008*

 Post CAT (n = 24)

14.1 ± 5.3 (n = 16)

19.6 ± 9.6 (n = 8)

0.136

Pre SF-36 component

 Physical functioning

49.5 ± 15.1 (n = 19)

40.9 ± 15.5 (n = 10)

0.308

 Role physical

37.6 ± 19.3 (n = 19)

38.1 ± 21.6 (n = 10)

0.456

 Bodily pain

44.8 ± 12.9 (n = 19)

41.4 ± 24.5 (n = 10)

0.804

 General health

45.3 ± 9.5 (n = 19)

45.4 ± 11.4 (n = 10)

0.946

 Vitality

43.2 ± 17.6 (n = 19)

39.0 ± 18.4 (n = 10)

0.804

 Social functioning

49.0 ± 11.2 (n = 19)

38.8 ± 17.3 (n = 10)

0.069

 Role emotional

41.3 ± 18.2 (n = 19)

40.7 ± 17.0 (n = 10)

0.604

 Mental health

49.3 ± 14.3 (n = 19)

38.4 ± 12.7 (n = 9)

0.061

 PCS

46.7 ± 5.8 (n = 19)

52.5 ± 9.7 (n = 7)

0.209

 MCS

51.2 ± 10.1 (n = 19)

45.5 ± 9.6 (n = 7)

0.073

 RCS

38.1 ± 12.4 (n = 19)

36.3 ± 23.3 (n = 7)

0.955

  1. Values are mean ± SD and compared by paired t-test, Mann-Whitney U test or Fisher’s exact test. *P < 0.05. aDesaturation was defined as a fall in SpO2 ≥ 4 % or SpO2 < 90 %. The HADS score ≥8 denotes a probable case. Pre preoperative, Post postoperative