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Table 8 Comparison of data with and without chemoradiotherapy

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

  Without (n = 12) Chemotherapy and/or radiotherapy (n = 22) P value
%FEV1 93.3 ± 20.4 94.5 ± 13.9 0.466
FEV1/FVC, % 69.8 ± 7.7 74.8 ± 7.8 0.136
Pre 6MWD, m 485 ± 59 499 ± 82 0.790
Desaturation during 6MWTa N = 4 N = 1 1
Post 6MWD, m 389 ± 109 421 ± 109 (n = 20) 0.654
Desaturation during 6MWTa N = 0 N = 5 0.155
Changes in 6MWD, m −97 ± 61 −78 ± 104 (n = 20) 0.158
Pre hand grip strength, kgf
 Right 33.0 ± 12.0 29.9 ± 7.4 0.327
 Left 31.8 ± 11.0 28.1 ± 7.8 0.261
Post hand grip strength, kgf
 Right 30.8 ± 11.3 (n = 11) 27.7 ± 7.0 0.560
 Left 28.4 ± 8.9 (n = 11) 27.1 ± 7.2 0.693
Pre isometric knee extensor muscle strength, kgf
 Right 30.0 ± 9.4 23.4 ± 7.0 (n = 20) 0.059
 Left 28.8 ± 11.6 23.0 ± 7.2 (n = 20) 0.269
Post isometric knee extensor muscle strength, kgf
 Right 28.3 ± 9.0 22.5 ± 7.0 (n = 20) 0.120
 Left 25.4 ± 8.8 21.3 ± 6.8 (n = 20) 0.287
 Pre HADS anxiety 4.9 ± 3.5 6.0 ± 2.6 (n = 19) 0.367
  Scores ≥8 N = 3 N = 4 1
 Pre HADS depression 4.5 ± 2.9 6.2 ± 3.7 (n = 19) 0.287
  Scores ≥8 N = 3 N = 5 1
 Post HADS anxiety 5.3 ± 4.8 (n = 7) 5.0 ± 3.8 (n = 16) 1
  Scores ≥8 N = 2 N = 6 1
 Post HADS depression 3.3 ± 2.6 (n = 7) 6.3 ± 4.0 (n = 16) 0.103
  Scores ≥8 N = 2 N = 9 0.682
 Pre CAT (n = 31) 9.3 ± 6.4 10.6 ± 6.1 (n = 19) 0.509
 Post CAT (n = 24) 13.7 ± 8.6 (n = 6) 16.7 ± 6.9 (n = 18) 0.343
Pre SF-36 component
 Physical functioning 51.7 ± 20.1 (n = 11) 43.4 ± 11.6 (n = 18) 0.146
 Role physical 46.2 ± 25.3 (n = 11) 32.6 ± 13.8 (n = 18) 0.084
 Bodily pain 38.7 ± 21.0 (n = 11) 46.7 ± 14.6 (n = 18) 0.387
 General health 49.2 ± 7.9 (n = 11) 42.9 ± 10.6 (n = 18) 0.055
 Vitality 48.1 ± 19.0 (n = 11) 37.9 ± 16.1 (n = 18) 0.188
 Social functioning 45.0 ± 18.1 (n = 11) 45.7 ± 11.7 (n = 18) 0.580
 Role emotional 50.2 ± 19.7 (n = 11) 35.5 ± 13.7 (n = 18) 0.049*
 Mental health 47.1 ± 17.4 (n = 10) 45.1 ± 13.2 (n = 18) 1.000
 PCS 53.2 ± 6.6 (n = 8) 46.0 ± 6.6 (n = 18) 0.019*
 MCS 48.9 ± 8.5 (n = 8) 50.0 ± 10.8 (n = 18) 0.807
 RCS 44.3 ± 11.3 (n = 8) 32.5 ± 16.0 (n = 18) 0.090
  1. Values are mean ± SD and compared by paired t-test, Mann-Whitney U test or Fisher’s exact test. aDesaturation was defined as a fall in SpO2 ≥ 4 % or SpO2 < 90 %