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Table 8 Comparison of data with and without chemoradiotherapy

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

 

Without (n = 12)

Chemotherapy and/or radiotherapy (n = 22)

P value

%FEV1

93.3 ± 20.4

94.5 ± 13.9

0.466

FEV1/FVC, %

69.8 ± 7.7

74.8 ± 7.8

0.136

Pre 6MWD, m

485 ± 59

499 ± 82

0.790

Desaturation during 6MWTa

N = 4

N = 1

1

Post 6MWD, m

389 ± 109

421 ± 109 (n = 20)

0.654

Desaturation during 6MWTa

N = 0

N = 5

0.155

Changes in 6MWD, m

−97 ± 61

−78 ± 104 (n = 20)

0.158

Pre hand grip strength, kgf

 Right

33.0 ± 12.0

29.9 ± 7.4

0.327

 Left

31.8 ± 11.0

28.1 ± 7.8

0.261

Post hand grip strength, kgf

 Right

30.8 ± 11.3 (n = 11)

27.7 ± 7.0

0.560

 Left

28.4 ± 8.9 (n = 11)

27.1 ± 7.2

0.693

Pre isometric knee extensor muscle strength, kgf

 Right

30.0 ± 9.4

23.4 ± 7.0 (n = 20)

0.059

 Left

28.8 ± 11.6

23.0 ± 7.2 (n = 20)

0.269

Post isometric knee extensor muscle strength, kgf

 Right

28.3 ± 9.0

22.5 ± 7.0 (n = 20)

0.120

 Left

25.4 ± 8.8

21.3 ± 6.8 (n = 20)

0.287

 Pre HADS anxiety

4.9 ± 3.5

6.0 ± 2.6 (n = 19)

0.367

  Scores ≥8

N = 3

N = 4

1

 Pre HADS depression

4.5 ± 2.9

6.2 ± 3.7 (n = 19)

0.287

  Scores ≥8

N = 3

N = 5

1

 Post HADS anxiety

5.3 ± 4.8 (n = 7)

5.0 ± 3.8 (n = 16)

1

  Scores ≥8

N = 2

N = 6

1

 Post HADS depression

3.3 ± 2.6 (n = 7)

6.3 ± 4.0 (n = 16)

0.103

  Scores ≥8

N = 2

N = 9

0.682

 Pre CAT (n = 31)

9.3 ± 6.4

10.6 ± 6.1 (n = 19)

0.509

 Post CAT (n = 24)

13.7 ± 8.6 (n = 6)

16.7 ± 6.9 (n = 18)

0.343

Pre SF-36 component

 Physical functioning

51.7 ± 20.1 (n = 11)

43.4 ± 11.6 (n = 18)

0.146

 Role physical

46.2 ± 25.3 (n = 11)

32.6 ± 13.8 (n = 18)

0.084

 Bodily pain

38.7 ± 21.0 (n = 11)

46.7 ± 14.6 (n = 18)

0.387

 General health

49.2 ± 7.9 (n = 11)

42.9 ± 10.6 (n = 18)

0.055

 Vitality

48.1 ± 19.0 (n = 11)

37.9 ± 16.1 (n = 18)

0.188

 Social functioning

45.0 ± 18.1 (n = 11)

45.7 ± 11.7 (n = 18)

0.580

 Role emotional

50.2 ± 19.7 (n = 11)

35.5 ± 13.7 (n = 18)

0.049*

 Mental health

47.1 ± 17.4 (n = 10)

45.1 ± 13.2 (n = 18)

1.000

 PCS

53.2 ± 6.6 (n = 8)

46.0 ± 6.6 (n = 18)

0.019*

 MCS

48.9 ± 8.5 (n = 8)

50.0 ± 10.8 (n = 18)

0.807

 RCS

44.3 ± 11.3 (n = 8)

32.5 ± 16.0 (n = 18)

0.090

  1. Values are mean ± SD and compared by paired t-test, Mann-Whitney U test or Fisher’s exact test. aDesaturation was defined as a fall in SpO2 ≥ 4 % or SpO2 < 90 %