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Table 9 Correlations between changes in 6MWD after esophagectomy and other parameters

From: Changes in exercise capacity, muscle strength, and health-related quality of life in esophageal cancer patients undergoing esophagectomy

Parameters Univariate analysis Multivariate analysis
Standardized partial regression coefficient P value Standardized partial regression coefficient P value
Preoperative parameters
 Body mass index −0.056 0.760 ND ND
 %VC −0.327 0.068 −0.573 (n = 23) 0.077
 %FEV1 −0.302 0.093 0.369 (n = 23) 0.273
 6MWD 0.153 0.403 ND ND
Hand grip strength
 Right 0.273 0.130 ND ND
 Left 0.254 0.162 ND ND
Isometric knee extensor muscle strength
 Right (n = 29) 0.028 0.885 ND ND
 Left (n = 29) −0.101 0.601 ND ND
 CAT (n = 29) 0.220 0.251 ND ND
SF-36 component
 Physical functioning (n = 27) −0.186 0.353 ND ND
 Role physical (n = 27) −0.008 0.968 ND ND
 Bodily pain (n = 27) 0.283 0.153 ND ND
 General health (n = 27) 0.049 0.809 ND ND
 Social functioning (n = 27) −0.217 0.276 ND ND
 Vitality (n = 27) 0.210 0.293 ND ND
 Role emotional (n = 27) 0.028 0.891 ND ND
 Mental health (n = 26) −0.145 0.480 ND ND
 PCS (n = 24) 0.437 0.033* 0.488 (n = 23) 0.027*
 MCS (n = 24) −0.073 0.734 ND ND
 RCS (n = 24) 0.115 0.593 ND ND
 With-without COPD 0.241 0.184 ND ND
 With-without chemo-radio therapy −0.103 0.575 ND ND
Intraoperative parameters
 Blood loss during surgery 0.145 0.428 ND ND
 Operation time 0.145 0.430 ND ND
Postoperative parameters
 Postoperative hospital stays 0.046 0.802 ND ND
Changes in hand grip strength
 Right (n = 31) 0.153 0.412 ND ND
 Left (n = 31) 0.143 0.442 ND ND
Changes in isometric knee extensor muscle strength
 Right (n = 29) 0.045 0.815 ND ND
 Left (n = 29) 0.089 0.646 ND ND
 Changes in CAT scores (n = 23) −0.219 0.315 ND ND
  1. The multivariate analysis includes relevant variables with P values <0.10 in univariate analysis (preoperative %VC and %FEV1, and PCS). ND not done. *P < 0.05. N = 32 otherwise indicated