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Fig. 1 | BMC Sports Science, Medicine and Rehabilitation

Fig. 1

From: Exercise as ‘precision medicine’ for insulin resistance and its progression to type 2 diabetes: a research review

Fig. 1

Prevalence of insulin resistance, obesity and type 2 diabetes in the US adult population. The complex interaction between insulin resistance, overweight/obesity and type 2 diabetes is exemplified by five distinct subsets of metabolically-compromised individuals that collectively comprise > 50% of the US adult population (grey shade). The fact that some of these individuals can fend off metabolic decline despite being obese while others possess type 2 diabetes and/or insulin resistance without obesity provides evidence that initiation and progression of type 2 diabetes is multi-factorial and complex. IS, insulin sensitive; IR, insulin resistant; T2D, type 2 diabetes; NW, normal weight; O, obese

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