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Fig. 4 | BMC Sports Science, Medicine and Rehabilitation

Fig. 4

From: Cardiac hypertrophy is stimulated by altered training intensity and correlates with autophagy modulation in male Wistar rats

Fig. 4

Autophagy Related mRNA Expression in Cardiac Muscles After 8 Weeks of Treadmill Training with Different Intensity. a 8 weeks of Treadmill Training with Different Intensity Modulates PIK3CA, mTOR, LC3, p62 mRNA Expression in Rat Cardiac Muscle (Left ventricle myocardium). b A significant decrease of PIK3CA mRNA Expression were found in LI and MI compared to control (a), and between LI and HI (b), MI and HI (c). c mTOR mRNA expression also significantly decreased in LI, MI and increased in HI compared to control (a), between LI and HI (b) and MI and HI (c). d LC3 mRNA expression also significantly decreased in LI, MI and HI compared to control (a), and between LI and HI (b). e p62 mRNA expression also significantly decreased in LI, MI and increased in HI compared to control (a), between LI and HI (b) and MI and HI (c). Data was presented as average mean ± standard error of mean (SEM) with p < 0.05 considered as significant (*), and p < 0.01 considered as very significant (**)

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