Skip to main content

Table 3 Clinical and biochemical behaviors independently modified by overtraining syndrome (OTS)

From: Novel causes and consequences of overtraining syndrome: the EROS-DISRUPTORS study

Parameters modified by the presence of OTS p of the influence of OTS a Level of influence of the presence of OTS a
(Adjusted R-Square)
Other variables that may also influence Equation for the estimation of the parameter level in male athletes
Late ACTH response to an ITT (30’after hypoglycaemia) (pg/mL) 0.002 19.9% none n/a
Late cortisol response (30’after hypoglycaemia) (μg/dL) 0.0005 26.1% none Cortisol (μg/dL) = 17.86–3.81(if OTS)
Cortisol response to an ITT (μg/dL) 0.002 22.0% none n/a
Late GH response (30’after hypoglycaemia) (μg/L) 0.001 23.0% none n/a
Testosterone-to-oestadiol ratio (T/E) 0.0002 30.7% none T/E = 14.1 + 12.9 (if OTS)
POMS vigour subscale < 0.0001 83.6% Sleep quality POMS vigour subscale = 3.7 + 1.15x(sleep quality) – 11.96(if OTS)
POMS fatigue subscale < 0.0001 85.7% Sleep quality POMS fatigue subscale = 24.5–0.9 x(sleep quality) + 15.3(if OTS)
POMS tension subscale < 0.0001 42.8% none Not able to be estimated 
Visceral fat (cm2) 0.002 38.2% Protein and overall calorie intake Visceral fat = 47.4–11.9x(protein intake) + 1.3x(calorie intake) + 45.1(if OTS)
Muscle mass (%) 0.028 33.7% Protein intake Muscle mass = 47.84 + 1.42x(protein intake) – 3.47(if OTS)
Body water (%) 0.001 50.5% Protein and overall calorie intake Body water = 60.75 + 1.69x(protein intake) – 0.12x(calorie intake) - 5.77(if OTS)
Neutrophils (/mm3) 0.015 13.8% Calorie intake Neutrophils = 4210–60.7x(calorie intake) + 154.4x(CHO intake) -1724(if OTS)
Neutrophil-to-lymphocyte ratio 0.015 13.6% none Ratio = 2.00–1.32(if OTS)
  1. CHO Carbohydrate, ITT Insulin tolerant test, POMS Profile of mood states, BMR Basal metabolic rate, T/E Testosterone-to-oestradiol, OTS Overtraining syndrome’, n/a non applicables (non-normal distribution)
  2. Calorie intake = kcal/kg/day, CHO intake = g(CHO)/kg/day; protein intake = g(protein)/kg/day; extra activities = working and/or studying hours besides training, sleep quality = self-reported sleep quality (0 to 10)
  3. aOther minor influences may also reflect the p-value and the level of influence