| Normoxic condition | Hypoxic condition | ANOVA | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
IMLET (n = 8) | ET (n = 8) | IMLET (n = 8) | ET (n = 8) |  | ||||||||
pre | Post | pre | post | pre | post | pre | post | condition | period | group | Interaction | |
VO2peak [L min− 1] | 3159 ± 464 | 3487 ± 635 | 2897 ± 498 | 3171 ± 489 | 2631 ± 433 | 2980 ± 569 | 2546 ± 424 | 2717 ± 489 | P = 0.00, ηp2 = 0.90 | P = 0.00, ηp2 = 0.55 | P = 0.34, ηp2 = 0.07 | P = 0.35, ηp2 = 0.06 |
VCO2peak [L min− 1] | 3422 ± 524 | 3752 ± 584 | 3298 ± 528 | 3360 ± 511 | 2924 ± 383 | 3356 ± 616 | 2914 ± 479# | 3045 ± 511 | P = 0.00, ηp2 = 0.82 | P = 0.00, ηp2 = 0.62 | P = 0.42, ηp2 = 0.05 | P = 0.82, ηp2 = 0.00 |
Wmax [kp] | 4.03 ± 0.51 | 4.28 ± 0.49 | 3.72 ± 0.53 | 3.97 ± 0.54 | 3.44 ± 0.44 | 3.75 ± 0.44 | 3.28 ± 0.53 | 3.47 ± 0.54 | P = 0.00, ηp2 = 0.80 | P = 0.00, ηp2 = 0.75 | P = 0.32, ηp2 = 0.07 | P = 0.23, ηp2 = 0.10 |
VEmax [L min− 1] | 109.6 ± 20.6 | 127.6 ± 23.1 | 106.2 ± 16.7 | 109.9 ± 19.7 | 104.8 ± 22.0 | 121.8 ± 25.0 | 103.6 ± 16.4 | 107.5 ± 19.7 | P = 0.08, ηp2 = 0.19 | P = 0.00, ηp2 = 0.70 | P = 0.00, ηp2 = 0.97 | P = 0.05, ηp2 = 0.83 |
fR [breath min− 1] | 50.9 ± 9.7 | 53.7 ± 11.7 | 49.2 ± 8.5 | 48.3 ± 9.3 | 48.9 ± 12.1 | 50.3 ± 11.8 | 50.4 ± 8.6 | 47.6 ± 9.3 | P = 0.27, ηp2 = 0.08 | P = 0.91, ηp2 = 0.00 | P = 0.66, ηp2 = 0.01 | P = 0.89, ηp2 = 0.01 |
VT [L] | 2.47 ± 0.33 | 2.81 ± 0.45 | 2.30 ± 0.38 | 2.42 ± 0.41 | 2.46 ± 0.24 | 2.85 ± 0.44 | 2.27 ± 0.43 | 2.66 ± 0.41 | P = 0.50, ηp2 = 0.03 | P = 0.01, ηp2 = 0.63 | P = 0.51, ηp2 = 0.03 | P = 0.58, ηp2 = 0.02 |
VE VO2− 1 | 34.58 ± 2.6 | 36.63 ± 2.86 | 37.08 ± 5.33 | 34.69 ± 5.04 | 39.61 ± 3.06 | 40.83 ± 3.80 | 40.89 ± 3.58 | 39.80 ± 5.04 | P = 0.01, ηp2 = 0.80 | P = 0.01, ηp2 = 0.93 | P = 0.89, ηp2 = 0.01 | P = 0.42, ηp2 = 0.05 |
VE VCO2− 1 | 31.9 ± 2.9 | 33.9 ± 2.2 | 32.4 ± 3.3 | 32.8 ± 3.4 | 35.6 ± 3.7 | 36.2 ± 2.7 | 35.7 ± 2.9 | 35.3 ± 3.4 | P = 0.00, ηp2 = 0.72 | P = 0.15, ηp2 = 0.14 | P = 0.79, ηp2 = 0.01 | P = 0.72, ηp2 = 0.01 |
PETCO2 [mmHg] | 40.9 ± 2.2 | 37.2 ± 2.3 | 40.0 ± 3.7 | 38.7 ± 3.1 | 36.6 ± 3.0 | 34.0 ± 2.1 | 36.4 ± 2.8 | 35.9 ± 2.9 | P = 0.00, ηp2 = 0.81 | P = 0.03, ηp2 = 0.48 | P = 0.77, ηp2 = 0.01 | P = 0.68, ηp2 = 0.01 |
WOB [J min− 1] | 276 ± 87 | 318 ± 98 | 258 ± 66 | 288 ± 97 | 235 ± 59 | 276 ± 85 | 231 ± 64 | 299 ± 97 | P = 0.80, ηp2 = 0.01 | P = 0.04, ηp2 = 0.28 | P = 0.32, ηp2 = 0.08 | P = 0.53, ηp2 = 0.03 |
PEpeak [cmH2O] | 24.5 ± 11.2 | 23.2 ± 7.0 | 26.8 ± 9.6 | 26.4 ± 11.2 | 22.1 ± 6.3# | 22.3 ± 12.6 | 21.6 ± 5.3 | 21.5 ± 11.2 | P = 0.01, ηp2 = 0.43 | P = 0.61, ηp2 = 0.02 | P = 0.93, ηp2 = 0.01 | P = 0.81, ηp2 = 0.01 |
PIpeak [cmH2O] | −27.9 ± 22.8 | −37.9 ± 9.7 | −35.6 ± 5.3 | −38.2 ± 10.0 | −33.8 ± 4.6 | −32.7 ± 8.7 | −34.0 ± 7.3 | −39.1 ± 8.3 | P = 0.78, ηp2 = 0.01 | P = 0.06, ηp2 = 0.25 | P = 0.48, ηp2 = 0.04 | P = 0.11, ηp2 = 0.19 |
PEFR [L sec− 1] | 6.39 ± 1.56 | 7.54 ± 1.46 | 6.66 ± 1.65 | 6.63 ± 1.39 | 5.81 ± 1.29 | 7.00 ± 1.53 | 5.35 ± 0.51 | 6.54 ± 1.39 | P = 0.02, ηp2 = 0.34 | P = 0.02, ηp2 = 0.36 | P = 0.49, ηp2 = 0.04 | P = 0.13, ηp2 = 0.17 |
HRmax [beat min− 1] | 185.5 ± 7 | 187.7 ± 7.5 | 184.3 ± 10.4 | 184.5 ± 14.4 | 175.1 ± 9.4 | 178.0 ± 8.0 | 180.4 ± 11.7 | 181.0 ± 14.4 | P = 0.00, ηp2 = 0.61 | P = 0.32, ηp2 = 0.61 | P = 0.65, ηp2 = 0.02 | P = 0.66, ηp2 = 0.02 |
SaO2 [%] | 96 ± 3 | 96 ± 2 | 96 ± 2 | 97 ± 2 | 82 ± 3# | 82 ± 4# | 83 ± 2# | 84 ± 2# | P = 0.00, ηp2 = 0.97 | P = 0.43, ηp2 = 0.04 | P = 0.53, ηp2 = 0.03 | P = 0.01, ηp2 = 0.91 |