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Table 2 Physical performance measures at baseline, three, six, and twelve months of follow-up in patients treated with whole-body vibration and teriparatide (intervention) compared to teriparatide alone (control)

From: The combined effect of parathyroid hormone (1–34) and whole-body vibration exercise on physical performance in OSteoporotic women (PaVOS study): a secondary analysis from a randomised controlled trial

  Intervention P change within group from baseline Control P change within group from baseline P change between groups from baseline
SPPB, point Mean ± sd   Mean ± sd   
Baseline 9.13 ± 1.96 n = 16   10.16 ± 1.82 n = 18   
Three months 10.35 ± 1.69 n = 14 0. 014* 10.17 ± 2.00 n = 18 1.000 0.065
Six months 9.46 ± 2.29 n = 15 0.128 10.17 ± 1.70 n = 17 0.742 0.372
Twelve months 9.57 ± 2.50 n = 14 0.043* 10.24 ± 1.82 n = 17 0.606 0.248
5xChairstand time, with arms, s
 Baseline 18.9 ± 7.9 n = 16   13.8 ± 4.6 n = 18   
 Three months 14.4 ± 6.9 n = 14 0.036* 13.0 ± 3.5 n = 18 0.395 0.117
 Six months 16.2 ± 6.3 n = 15 0.085 13.4 ± 3.7 n = 17 0.572 0.185
 Twelve months 15.7 ± 9.8 n = 14 0.040* 15.3 ± 6.6 n = 17 0.341 0.037
Time 3 m walk, s
 Baseline 2.9 ± 0.7 n = 17   2.8 ± 0.9 n = 18   
  Three months 2.7 ± 0.5 n = 15 0.722 2.8 ± 0.8 n = 18 0.848 0.896
 Six months 3.0 ± 1.0 n = 15 0.977 2.8 ± 0.9 n = 17 0.912 0.956
 Twelve months 3.4 ± 1.8 n = 15 0.049* 2.7 ± 0.8 n = 17 0.622 0.077
Tandem total, s
 Baseline 27.8 ± 4.6 n = 17   28.8 ± 2.8 n = 18   
 Three months 28.3 ± 2.5 n = 15 0.525 28.4 ± 3.0 n = 18 0.680 0.470
 Six months 28.8 ± 2.4 n = 15 0.400 27.7 ± 3.1 n = 17 0.255 0.177
 Twelve months 28.9 ± 2.3 n = 15 0.191 28.3 ± 2.9 n = 17 0.226 0.094
TUG, s
 Baseline 10.7 ± 3.2 n = 17   9.6 ± 3.1 n = 18   
 Three months 9.2 ± 2.5 n = 15 0.257 9.2 ± 2.8 n = 18 0.580 0.650
 Six months 10.0 ± 4.3 n = 15 0.395 9.3 ± 4.3 n = 17 0.668 0.746
 Twelve months 11.4 ± 7.2 n = 15 0.394 8.95 ± 2.9 n = 17 0.344 0.205
Leg extension power, W/kg
 Baseline 0.91 ± 0.37 n = 17   1.10 ± 0.43 n = 18   
 Three months 1.07 ± 0.42 n = 15 0.175 1.24 ± 0.48 n = 18 0.026* 0.606
 Six months 1.13 ± 0.50 n = 15 0.010* 1.27 ± 0.64 n = 17 0.017* 0.798
 Twelve months 1.08 ± 0.49 n = 15 0.044* 1.36 ± 0.53 n = 17 0.000* 0.339
Total Lean mass, kg  
 Baseline 38.53 ± 6.56 n = 17   37.04 ± 3.88 n = 18   
 Twelve months 38.20 ± 6.65 n = 15 0.281 37.04 ± 4.84 n = 17 0.657 0.276
Appendicular lean mass index kg/m2
 Baseline 5.89 ± 0.76 n = 17   6.10 ± 0.89 n = 18   
 Twelve months 5.84 ± 0.66 n = 15 0.421 6.13 ± 0.92 n = 17 0.692 0.391
  1. P values are derived from a mixed linear regression model with time, time x treatment interaction and adjustment for baseline group values, or robust cluster regression model with time, time x treatment and adjustment for baseline group values with clusters for repeated measurements.*Indicates a significant change p < 0,05. n = number participants, SPPB short physical performance battery, TUG timed up and go