High-intensity interval training accelerates oxygen uptake kinetics and improves exercise tolerance for individuals with cystic fibrosis

Table 4 Pre-/post-training measurements during constant-work-rate test at 70% of peak work rate for O2+ and AMB groups

	O2+		AMB		Time	Group x Time
	Pre	Post	Pre	Post	P	P
Baseline V̇O₂ (L^.min^− 1)	0.40 ± 0.07	0.41 ± 0.08	0.37 ± 0.06	0.37 ± 0.10	0.864	0.924
V̇O₂ MRT (s)	61 ± 6	51 ± 14	64 ± 18	58 ± 29	0.168	0.699
V̇O₂ amplitude (L^.min^− 1)	1.03 ± 0.41	0.99 ± 0.44	1.09 ± 0.58	1.06 ± 0.59	0.211	0.830
∆V̇O_{2 (6-3)} (L^.min^− 1)	0.11 ± 0.07	0.14 ± 0.14	0.11 ± 0.07	0.05 ± 0.08	0.625	0.068
Isotime V̇_E (L^.min^− 1)	58 ± 17	48 ± 12	46 ± 8	45 ± 10	0.006*	0.026*
Isotime V_T (L)	1.5 ± 0.7	1.4 ± 0.6	1.6 ± 0.9	1.5 ± 0.9	0.054	0.281
Isotime BR (br^.min^− 1)	42 ± 8	36 ± 7	36 ± 14	37 ± 16	0.041*	0.006*
Isotime SpO₂%	90 ± 6	91 ± 4	90 ± 9	89 ± 7	0.668	0.413
Isotime [lactate] (mmol^. L^− 1)	6.3 ± 1.4	4.5 ± 0.9	5.2 ± 1.4	4.5 ± 0.6	0.003*	0.102
Isotime RPE	14.4 ± 1.9	11.8 ± 1.8	13.8 ± 1.5	14.8 ± 2.9	0.213	0.018*
Isotime dyspnea	5.0 ± 1.9	4.0 ± 1.0	4.0 ± 1.2	4.5 ± 1.7	0.601	0.145
Limit of tolerance (min)	11 ± 2	25 ± 6	12 ± 6	18 ± 11	0.002*	0.143

Values are presented as mean ± SD. MRT Mean response time, ∆V̇O_{2 (6-3)} change in V̇O₂ from minute 3 to 6, V̇_E, rate of minute ventilation, V_T Tidal volume, BR Breathing rate, SpO₂ peripheral capillary O₂ saturation saturation, [lactate] blood lactate concentration, RPE Rating of perceived exertion; * P < 0.05

ISSN: 2052-1847