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Table 4 Patient-reported outcomes with change score and standardised response mean. Values are mean (SD) unless otherwise noted

From: LOAD-intensity and time-under-tension of exercises for men who have Achilles tendinopathy (the LOADIT trial): a randomised feasibility trial

 

High Load

Low Load

 

with High TUT

with Low TUT

with High TUT

with Low TUT

Self-reported measures

Severity of pain using VISA-A a / 100

 Baseline

55.3 (13.4)

44.8 (18.1)

46.0 (15.8)

54.7 (9.8)

 Week-6

69.3 (14.8)

65.2 (16.7)

63.2 (16.8)

68.5 (14.0)

 Week-12

81.5 (11.2)

80.7 (17.5)

86.3 (9.0)

83.8 (13.0)

 Change score at 6-weeks, [95%CI]

14.0 [11,17]

15.0 [11,19]

17.2 [14,20]

14.0 [11,17]

 Change score at 12-weeks, [95%CI]

22.0 [19,25]

22.4 [19,25]

40.3 [37,43]

29.2 [26,32]

 SRM baseline-week 6

0.9

0.5

1.3

1.0

 SRM baseline-week 12

1.4

0.6

2.2

2.1

Worst pain using Numerical Pain Rating Scale / 10b

 Baseline

5.0 (2.2)

4.8 (3.2)

4.7 (3.0)

5.0 (3.0)

 Week-6

2 .4 (2.5)

2 .2 (1.0)

3.1 (2.2)

3.3 (2.2)

 Week-12

3 .4 (2.7)

2.3 (2.0)

2.1 (2.3)

2.3 (1.8)

 Change score at 6-weeks, [95%CI]

−3.0 [−4.-2]

−2.0 [−4.-1]

−2.0 [− 4,1]

−1.1 [− 2.1]

 Change score at 12-weeks, [95%CI]

− 2.1 [− 3,1]

−4.0 [−5,-2]

−2.0 [− 5,-0.5]

−2.5 [− 5,-1]

 SRM baseline-week 6

− 1.2

− 0.7

− 0.5

− 0.4

 SRM baseline-week 12

− 1.1

− 0.9

− 0.8

−0.9

EQ-5D-5L, Index c/ 1

 Baseline

0.71 (0.10)

0.71 (0.17)

0.72 (0.10)

0.74 (0.10)

 Week-6

0.79 (0.09)

0.76 (0.16)

0.76 (0.10)

0.78 (0.14)

 Week-12

0.84 (0.11)

0.88 (0.14)

0.84 (0.11)

0.87 (0.12)

 Change score at 6-weeks, [95%CI]

0.08 [0.1,0.3]

0.04 [−0.2,0.3]

0.02 [− 0.12,0]

0.03 [− 0.2,3]

 Change score at 12-weeks, [95%CI]

0.14 [0.1,0.5]

0.2 [− 0.1,0.3]

0.12 [− 0.1,0.3]

0.13 [0,0.3]

 SRM baseline-week 6

0.8

0.2

0.2

0.3

 SRM baseline-week 12

1.1

1.0

1.1

1.1

EQ-5D-5L, VAS d / 100

 Baseline

67.8 (15.2)

70.2 (17.8)

72.8 (16.6)

69.6 (12.0)

 Week-6

82.2 (8.5)

75.3 (9.4)

80.0 (8.3)

75.7 (13.6)

 Week-12

83.4 (13.2)

82.6 (15.5)

82.3 (10.3)

74.0 (11.5)

 Change score at 6-weeks, [95%CI]

15.0 [12,18]

6.4 [5,8]

7.0 [4,10]

6.0 [4,8]

 Change score at 12-weeks, [95%CI]

19.0 [16,22]

14.0 [12,14]

9.0 [7,11]

4.0 [2,6]

 SRM baseline-week 6

0.9

0.6

0.4

0.8

 SRM baseline-week 12

0.9

2.0

1.0

0.4

7-Day Activity Recall e

 Baseline

1041 (170)

1322 (257)

1017 (200)

1303 (296)

 Week-6

1071 (241)

1311 (237)

997 (194)

1229 (256)

 Week-12

837 (555)

1314 (211)

1046 (175)

1275 (285)

 Change score at 6-weeks, [95%CI]

29.3 [19,40]

−11.0 [−23,2]

−20.0 [−29,-11]

74.0 [− 62,-86]

 Change score at 12-weeks, [95%CI]

86.2 [82,96]

−3.0 [− 15,5]

29.0 [− 29,-10]

− 28 [−62,-86]

 SRM baseline-week 6

0.1

0

0

0

 SRM baseline-week 12

0.3

0

0.2

0

Tampa Scale for Kinesiophobia f/ 68

 Baseline

39.8 (8.7)

39.7 (3.6)

37.2 (4.9)

35.1 (12.5)

 Week-6

34.5 (8.3)

35.0 (6.1)

34.9 (4.1)

30.8 (6.8)

 Week-12

30.2 (6.4)

29.3 (6.1)

32.3 (6.4)

27.2 (4.5)

 Change score at 6-weeks, [95%CI]

−5.2[−8,-2]

−5.0[−7,-3]

−2.3[−4,1]

−4.3[−7,-2]

 Change score at 12-weeks, [95%CI]

−12.1[−14,-10]

−10.4[−12,-9]

− 5.0[−7,-3]

− 8.0[− 11,-5]

 SRM baseline-week 6

−0.6

−0.6

−0.7

−0.5

 SRM baseline-week 12

− 2.0

− 1.4

−0.6

−0.6

Pain Catastrophising Scale g/ 52

 Baseline

12.8 (6.4)

17.3 (16.5)

9.4 (7.7)

11.4 (11.3)

 Week-6

6.9 (3.2)

8.0 (7.0)

7.3 (5.9)

6.1 (5.4)

 Week-12

4.3 (4.2)

5.6 (6.2)

5.3 (5.9)

2.7 (2.1)

 Change score at 6-weeks, [95%CI]

−6.0[−8,-4]

−10.2[− 13,-7]

−2.2[−4,-1]

−5.3[− 8,-3]

 Change score at 12-weeks, [95%CI]

−8.0[− 10,-7]

−13.0[− 16,-10]

− 4.2[− 6,-2]

−9.0[− 11,-6]

 SRM baseline-week 6

−1.2

− 0.7

− 0.3

− 0.5

 SRM baseline-week 12

−1.3

− 0.7

− 0.5

− 0.8

Patient Impression of Change for pain h,i

 Week-6 (improve)

8 (67)

9 (82)

5 (42)

8 (67)

 Week-12 (improve)

7 (78)

10 (100)

10 (91)

9 (82)

Patient Impression of Change for function h,i

 Week-6 (improve)

7 (58)

8 (73)

4 (33)

9 (75)

 Week-12 (improve)

7 (78)

10 (100)

10 (91)

9 (100)

Patient-Acceptable Symptom State instrument for satisfaction i

 Week-6 (50% improve)

5 (42)

1 (10)

4 (33)

5 (42)

 Week-6 (100% improve)

7 (58)

9 (90)

8 (67)

7 (58)

 Week-12 (50% improve)

2 (22)

0

2 (18)

2 (17)

 Week-12 (100% improve)

7 (78)

10 (100)

9 (82)

10 (83)

  1. Abbreviations: aScores on the VISA–A range from 0 (worst Achilles symptoms) to 100 (no Achilles tendinopathy). b worst pain during the week scored on the NPRS range from 0 (no pain) to 10 (worst pain imaginable). cScores on the EQ-5D-5L Index Value range from < 0 (worse than dead) to 0 (dead) to 1 (full health). dScores on the EQ-5D-5L VAS range from 0 (worst imaginable health state) to 100 (best imaginable health state). eScores on the PAR are represented as daily energy expenditure (kilocalories per day). f Tampa score ranges from 17 (no fear of movement) to 68 (greater fear of movement). g Scores on CPS range from 0 (no pain) to 52 (higher levels of pain catastrophising). h dichotomised scores to “improved” and “not improved”. in (%)
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BMC Sports Science, Medicine and Rehabilitation

ISSN: 2052-1847

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