Skip to main content

Table 2 Training effects

From: Effectiveness and safety of a simple home-based rehabilitation program in pulmonary arterial hypertension: an interventional pilot study

  Baseline (t1) time 1 → 2 Post-intervention (t2) time 2 → 3 Post-observation (t3) time 1 → 3
change p-value change p-value change p-value
Functional parameters
 PImax, cmH2O 45.31 ± 23.82 16.38 0.002 61.69 ± 25.44 8.25 0.01 69.94 ± 29.83 24.62 < 0.001
 PEmax, cmH2O 70.94 ± 32.75 25.81 0.001 96.75 ± 40.93 5.38 NS 102.12 ± 36.69 31.19 < 0.001
 Dominant hand grip strength, kg 37.67 ± 12.32 5.67 0.017 43.33 ± 13.58 −1.8 NS 41.53 ± 15.81 3.87 NS
 Nondominant hand grip strength, kg 36.2 ± 14.35 4.47 0.015 40.67 ± 13.95 −4.33 0.003 36.33 ± 14.21 0.13 NS
 6MWD, m 436.81 ± 81.69 71.38 0.004 508.19 ± 87.97 −14.25 NS 493.94 ± 114.71 57.12 0.043
 SaO2, % (before 6MWT) 90.12 ± 4.72 2.31 0.029 92.44 ± 5.3 −1.94 NS 90.5 ± 6.96 0.38 NS
 SaO2, % (after 6MWT) 80.62 ± 12.38 2.44 NS 83.06 ± 11.24 −1.81 NS 81.25 ± 10.07 0.62 NS
 Dyspnea (before 6MWT) 0.81 ± 0.83 −0.69 0.011 0.12 ± 0.34 − 0.06 NS 0.06 ± 0.25 − 0.75 0.006
 Dyspnea (after 6MWT) 6 ± 2 −1.25 NS 4.75 ± 1.81 0.06 NS 4.81 ± 1.94 −1.19 NS
 Fatigue (before 6MWT) 0.5 ± 0.73 −0.38 NS 0.12 ± 0.34 0.19 NS 0.31 ± 0.79 −0.19 NS
 Fatigue (after 6MWT) 6.06 ± 1.95 −0.81 NS 5.25 ± 2.35 −0.5 NS 4.75 ± 2.24 −1.31 0.01
Body Mass Composition
 Weight, kg 75.29 ± 19.1 0.69 NS 75.98 ± 18.83 0.55 NS 76.53 ± 19.8 1.24 NS
 Body Mass Index, kg/m2 25.79 ± 5.78 0.34 NS 26.12 ± 5.53 0.18 NS 26.31 ± 5.96 0.52 NS
 Waist-Hip Ratio (WHR) 0.96 ± 0.12 0 NS 0.96 ± 0.12 0.1 NS 0.95 ± 0.13 0.1 NS
 Skeletal Muscle Mass, kg 27.54 ± 6.43 0.66 NS 28.2 ± 6.51 0.28 NS 28.48 ± 6.92 0.94 NS
 Body Fat Mass, kg 24.54 ± 11.17 −0.1 NS 24.44 ± 10.61 0.1 NS 24.54 ± 10.2 −0.01 NS
 Percentage of Body Fat, % 31.32 ± 9.08 −0.19 NS 31.14 ± 8.8 0.01 NS 31.14 ± 7.85 −0.18 NS
 Arm Circumference 32.28 ± 5.47 0.22 NS 32.5 ± 5.37 −0.06 NS 32.34 ± 5.36 0.16 NS
 Arm Muscle Circumference 25.29 ± 4.11 0.43 0.005 25.73 ± 4.04 −0.21 NS 25.51 ± 3.99 0.22 NS
SF-36
 Physical Functioning 55 ± 28.81 12.81 < 0.001 67.81 ± 24.76 −3.75 NS 64.06 ± 24.17 9.07 NS
 Role Physical 50 ± 29.4 17.97 0.015 67.97 ± 25.81 −8.59 NS 59.38 ± 26.02 9.38 NS
 Bodily Pain 63.38 ± 29.6 6.56 NS 69.94 ± 28.74 3.62 NS 73.56 ± 24.39 10.19 NS
 General Health 41.06 ± 24.06 4.19 NS 45.25 ± 18.83 −1.94 NS 43.31 ± 17.37 2.25 NS
 Vitality 50.39 ± 24.52 10.55 0.022 60.94 ± 18.61 −2.34 NS 58.59 ± 21.27 8.2 NS
 Social Functioning 66.41 ± 28.77 4.69 NS 71.09 ± 22.69 0.78 NS 71.88 ± 27.2 5.47 NS
 Role Emotional 69.27 ± 32.16 13.02 0.029 82.29 ± 20.61 −4.17 NS 78.13 ± 27.87 8.86 NS
 Mental Health 68.75 ± 22.55 0.94 NS 69.69 ± 19.1 −1.56 NS 68.12 ± 18.25 −0.62 NS
 Physical Component Summary 40.11 ± 11.35 4.66 0.005 44.77 ± 9.05 −0.98 NS 43.79 ± 8.13 3.68 NS
 Mental Component Summary 47.55 ± 13.33 2.07 NS 49.63 ± 9.27 −0.75 NS 48.88 ± 11.27 1.33 NS
Fatigue Severity Scale 4.08 ± 1.6 −0.7 NS 3.38 ± 1.5 0.24 NS 3.61 ± 1.5 −0.47 NS
  1. Values are mean ± standard deviation
  2. 6MWD: 6-min walk distance; 6MWT: 6-min walk test; NS: not significant; PEmax, maximal expiratory pressure; PImax, maximal inspiratory pressure; SaO2: oxygen saturation; SF-36: 36-Item short form health survey; time 1: measurements before intervention period; time 2: measurements after intervention period; time 3: measurements after observation period