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Table 2 Training effects

From: Effectiveness and safety of a simple home-based rehabilitation program in pulmonary arterial hypertension: an interventional pilot study

 

Baseline (t1)

time 1 → 2

Post-intervention (t2)

time 2 → 3

Post-observation (t3)

time 1 → 3

change

p-value

change

p-value

change

p-value

Functional parameters

 PImax, cmH2O

45.31 ± 23.82

16.38

0.002

61.69 ± 25.44

8.25

0.01

69.94 ± 29.83

24.62

< 0.001

 PEmax, cmH2O

70.94 ± 32.75

25.81

0.001

96.75 ± 40.93

5.38

NS

102.12 ± 36.69

31.19

< 0.001

 Dominant hand grip strength, kg

37.67 ± 12.32

5.67

0.017

43.33 ± 13.58

−1.8

NS

41.53 ± 15.81

3.87

NS

 Nondominant hand grip strength, kg

36.2 ± 14.35

4.47

0.015

40.67 ± 13.95

−4.33

0.003

36.33 ± 14.21

0.13

NS

 6MWD, m

436.81 ± 81.69

71.38

0.004

508.19 ± 87.97

−14.25

NS

493.94 ± 114.71

57.12

0.043

 SaO2, % (before 6MWT)

90.12 ± 4.72

2.31

0.029

92.44 ± 5.3

−1.94

NS

90.5 ± 6.96

0.38

NS

 SaO2, % (after 6MWT)

80.62 ± 12.38

2.44

NS

83.06 ± 11.24

−1.81

NS

81.25 ± 10.07

0.62

NS

 Dyspnea (before 6MWT)

0.81 ± 0.83

−0.69

0.011

0.12 ± 0.34

− 0.06

NS

0.06 ± 0.25

− 0.75

0.006

 Dyspnea (after 6MWT)

6 ± 2

−1.25

NS

4.75 ± 1.81

0.06

NS

4.81 ± 1.94

−1.19

NS

 Fatigue (before 6MWT)

0.5 ± 0.73

−0.38

NS

0.12 ± 0.34

0.19

NS

0.31 ± 0.79

−0.19

NS

 Fatigue (after 6MWT)

6.06 ± 1.95

−0.81

NS

5.25 ± 2.35

−0.5

NS

4.75 ± 2.24

−1.31

0.01

Body Mass Composition

 Weight, kg

75.29 ± 19.1

0.69

NS

75.98 ± 18.83

0.55

NS

76.53 ± 19.8

1.24

NS

 Body Mass Index, kg/m2

25.79 ± 5.78

0.34

NS

26.12 ± 5.53

0.18

NS

26.31 ± 5.96

0.52

NS

 Waist-Hip Ratio (WHR)

0.96 ± 0.12

0

NS

0.96 ± 0.12

0.1

NS

0.95 ± 0.13

0.1

NS

 Skeletal Muscle Mass, kg

27.54 ± 6.43

0.66

NS

28.2 ± 6.51

0.28

NS

28.48 ± 6.92

0.94

NS

 Body Fat Mass, kg

24.54 ± 11.17

−0.1

NS

24.44 ± 10.61

0.1

NS

24.54 ± 10.2

−0.01

NS

 Percentage of Body Fat, %

31.32 ± 9.08

−0.19

NS

31.14 ± 8.8

0.01

NS

31.14 ± 7.85

−0.18

NS

 Arm Circumference

32.28 ± 5.47

0.22

NS

32.5 ± 5.37

−0.06

NS

32.34 ± 5.36

0.16

NS

 Arm Muscle Circumference

25.29 ± 4.11

0.43

0.005

25.73 ± 4.04

−0.21

NS

25.51 ± 3.99

0.22

NS

SF-36

 Physical Functioning

55 ± 28.81

12.81

< 0.001

67.81 ± 24.76

−3.75

NS

64.06 ± 24.17

9.07

NS

 Role Physical

50 ± 29.4

17.97

0.015

67.97 ± 25.81

−8.59

NS

59.38 ± 26.02

9.38

NS

 Bodily Pain

63.38 ± 29.6

6.56

NS

69.94 ± 28.74

3.62

NS

73.56 ± 24.39

10.19

NS

 General Health

41.06 ± 24.06

4.19

NS

45.25 ± 18.83

−1.94

NS

43.31 ± 17.37

2.25

NS

 Vitality

50.39 ± 24.52

10.55

0.022

60.94 ± 18.61

−2.34

NS

58.59 ± 21.27

8.2

NS

 Social Functioning

66.41 ± 28.77

4.69

NS

71.09 ± 22.69

0.78

NS

71.88 ± 27.2

5.47

NS

 Role Emotional

69.27 ± 32.16

13.02

0.029

82.29 ± 20.61

−4.17

NS

78.13 ± 27.87

8.86

NS

 Mental Health

68.75 ± 22.55

0.94

NS

69.69 ± 19.1

−1.56

NS

68.12 ± 18.25

−0.62

NS

 Physical Component Summary

40.11 ± 11.35

4.66

0.005

44.77 ± 9.05

−0.98

NS

43.79 ± 8.13

3.68

NS

 Mental Component Summary

47.55 ± 13.33

2.07

NS

49.63 ± 9.27

−0.75

NS

48.88 ± 11.27

1.33

NS

Fatigue Severity Scale

4.08 ± 1.6

−0.7

NS

3.38 ± 1.5

0.24

NS

3.61 ± 1.5

−0.47

NS

  1. Values are mean ± standard deviation
  2. 6MWD: 6-min walk distance; 6MWT: 6-min walk test; NS: not significant; PEmax, maximal expiratory pressure; PImax, maximal inspiratory pressure; SaO2: oxygen saturation; SF-36: 36-Item short form health survey; time 1: measurements before intervention period; time 2: measurements after intervention period; time 3: measurements after observation period