Table 2 Evidence assessment of outcomes
Outcomes | Anticipated absolute effects (95% CI) | Patients (studies) | Quality of evidence | Rated down reasons |
|---|---|---|---|---|
Function ability | 0.25 MD lower (0.38–0.11 lower) | 735 (11 RCTs) | ⨁⨁⨁◯ Moderate | Inconsistency |
Disease activity | 0.55 MD lower (1.12 lower to 0.01 higher) | 573 (8 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |
Joint counts | 0.59 MD lower (1.26 lower to 0.07 higher) | 305 (4 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |
CRP | 1.08 MD lower (2.20 lower to 0.05 higher) | 298 (5 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |
ESR | 0.76 SMD lower (1.67 lower to 0.14 higher) | 305 (5 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |
pain | 0.46 SMD lower (0.90–0.01 lower) | 247 (4 RCTs) | ⨁⨁⨁◯ Moderate | Imprecision |
Aerobic capacity | 2.41 MD higher (1.36–3.45 higher) | 247 (5 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |
STS test | 1.60 MD higher (0.07–3.13 higher) | 122 (2 RCTs) | ⨁⨁◯◯ Low | Inconsistency; imprecision |