Three-week exercise and protein intake immediately after exercise increases the 6-min walking distance with simultaneously improved plasma volume in patients with chronic cerebrovascular disease: a preliminary prospective study

Table 5 Body weight, cardiovascular responses, physical fitness, and walking performance before and after 3-week rehabilitation in both groups

Measurements	PG (n = 8)		CG (n = 8)		P values
Measurements	Before	After	Before	After	Time Group Group × Time
Body weight, kg	54.5 (6.5)	52.9 (6.2)†	57.5 (10.8)	55.4 (9.5)†	0.004 0.532 0.639
Systolic blood pressure, mmHg	119.8 (17.6)	121.9 (17.6)	128.3 (11.3)	120.9 (10.8)	0.401 0.584 0.139
Diastolic blood pressure, mmHg	82.0 (12.2)	81.1 (15.3)	88.5 (7.9)	76.3 (11.5)	0.046 0.878 0.079
Pulse pressure, mmHg	37.8 (9.4)	40.8 (12.7)	39.8 (10.0)	44.6 (13.7)	0.274 0.538 0.790
Mean arterial pressure, mmHg	94.6 (13.5)	94.7 (15.0)	101.8 (7.8)	91.1 (9.2) †	0.052 0.737 0.052
Rate-pressure product	8713 (1780)	8864 (1781)	9749 (1583)	8798 (1519) †	0.129 0.553 0.043
Heart rate, beats/min
Rest	72.6 (8.6)	72.8 (10.0)	76.6 (14.4)	72.8 (10.0)	0.307 0.706 0.277
Peak	125 (21)	127 (19)	127 (18)	125 (19) ¶	0.976 0.978 0.694
VO₂, mL/kg/min
Rest	4.8 (1.2)	4.4 (0.9)	5.9 (1.3)	5.2 (1.3)	0.049 0.109 0.514
Peak	17.7 (3.9)	19.3 (2.2)†	19.6 (4.0)	21.2 (4.4)†	0.035 0.276 0.994
VO₂, mL/min
Peak	956.1 (211.1)	1022.0 (182.0)	1134.8 (335.8)	1187.7 (340.2)	0.136 0.217 0.866
Knee-extensor strength, Nm
Paralyzed	35.9 (13.7)	39.6 (13.8)†	33.6 (6.7)	36.8 (5.7)†	0.001 0.636 0.798
Non-paralyzed	48.2 (10.2)	48.9 (10.6)	43.9 (8.0)	44.2 (6.2)	0.532 0.322 0.826
6MWD, m	288 (106)	342 (108)†	281 (110)	296 (117)	0.001 0.641 0.037
10MWS, m/sec
Optimum	0.84 (0.32)	0.95 (0.31)†	0.78 (0.25)	0.85 (0.33)	0.019 0.597 0.530
Maximum	1.12 (0.42)	1.26 (0.40)	1.08 (0.49)	1.09 (0.55)	0.116 0.116 0.181

Values are shown as mean (SD) in the intervention (PG) and control groups (CG). Systolic (SBP) and diastolic blood pressure (DBP) were measured at rest before cardiopulmonary exercise testing. The heart rate at peak was recorded during cardiopulmonary exercise testing in 8 and 7 participants (¶) in PG and CG, respectively. The pulse pressure was calculated as SBP – DBP. The mean arterial pressure was calculated as DBP + (SBP − DBP)/3. The rate-pressure product was calculated as the heart rate × SBP. VO₂, oxygen consumption rate; 6MWD, 6-min walking distance; 10MWS, 10-m walking speed; †, compared with the baseline before the onset of rehabilitation program at the level of P < 0.05, as determined by the paired t-test
P values of the effects of group and time and interaction group and time from two-way ANOVA repeated measurement are shown

ISSN: 2052-1847