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Table 4 Baseline determinants of membership to the three identified overall adherence clusters

From: Patterns and determinants of adherence to resistance and endurance training during cancer treatment in the Phys-Can RCT

 

Randomised to low-moderate intensity training

Randomised to high intensity training

Low (n = 33) versus high adherence (n = 88) clusters

Mixed (n = 54) versus high adherence (n = 88) clusters

Low (n = 48) versus high adherence (n = 69) clusters

Mixed (n = 58) versus high adherence (n = 69) clusters

RRR

LCI

UCI

P value

RRR

LCI

UCI

P value

RRR

LCI

UCI

P value

RRR

LCI

UCI

P value

Age

0.86

0.77

0.96

0.008

1.01

0.94

1.08

0.877

0.83

0.74

0.93

0.001

0.94

0.87

1.02

0.115

Breast cancer

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Colorectal cancer

2.18

0.07

67.2

0.657

16.9

1.37

208.2

0.027

0.00

0.00

 

0.992

5.86

0.12

283.3

0.372

Prostate cancer

1.24

0.07

20.8

0.880

13.8

1.90

99.4

0.009

0.59

0.04

8.10

0.691

4.12

0.62

27.2

0.142

Linköping

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Lund

3.99

0.51

31.3

0.188

1.53

0.34

6.93

0.582

60.4

3.60

1011.5

0.004

2.17

0.47

9.98

0.321

Uppsala

3.34

0.30

36.7

0.325

0.37

0.08

1.73

0.207

6.38

0.45

90.8

0.172

0.27

0.06

1.19

0.082

with behaviour change support

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

without behaviour change support

0.11

0.02

0.56

0.008

1.96

0.72

5.31

0.188

0.20

0.05

0.85

0.029

1.11

0.40

3.09

0.842

Chemotherapy

NO

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Chemotherapy

YES

0.89

0.12

6.33

0.905

0.81

0.22

3.02

0.754

0.19

0.03

1.15

0.070

1.25

0.33

4.76

0.739

Comorbidity

NO

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Comorbidity

YES

1.41

0.36

5.58

0.627

0.84

0.30

2.40

0.751

1.33

0.33

5.37

0.690

1.24

0.44

3.52

0.683

VO2 max

0.81

0.69

0.94

0.006

0.97

0.89

1.07

0.582

0.80

0.69

0.92

0.001

0.91

0.83

1.01

0.067

Endurance training maintenance

NO

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Endurance training maintenance

YES

0.17

0.02

1.25

0.081

0.41

0.11

1.49

0.177

0.26

0.04

1.82

0.174

0.74

0.21

2.59

0.639

Strength training maintenance

NO

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

1.00

1.00

1.00

 

Strength training maintenance

YES

7.00

0.52

94.3

0.143

0.25

0.04

1.41

0.115

1.64

0.11

25.51

0.724

1.47

0.36

6.01

0.589

MFI general fatigue

1.15

0.84

1.58

0.376

1.01

0.80

1.27

0.938

0.68

0.45

1.01

0.058

1.13

0.88

1.44

0.338

MFI physical fatigue

0.99

0.77

1.28

0.955

0.80

0.63

1.00

0.054

1.94

1.23

3.05

0.004

0.94

0.74

1.21

0.643

MFI reduced action

0.48

0.31

0.73

0.001

0.76

0.58

1.00

0.046

0.69

0.52

0.93

0.014

0.93

0.74

1.16

0.506

MFI reduced motivation

1.30

0.95

1.78

0.099

1.28

1.01

1.63

0.042

0.86

0.65

1.13

0.279

0.95

0.77

1.18

0.670

MFI mental fatigue

1.31

0.95

1.79

0.100

1.36

1.08

1.72

0.010

1.16

0.87

1.55

0.323

1.13

0.90

1.43

0.304

Global health status/quality of life

0.95

0.90

1.00

0.041

0.94

0.91

0.99

0.009

0.93

0.88

0.98

0.007

0.99

0.95

1.03

0.728

Physical function

1.01

0.93

1.09

0.787

0.99

0.93

1.04

0.603

0.97

0.90

1.04

0.388

1.01

0.95

1.06

0.802

Role function

1.05

1.00

1.09

0.036

1.01

0.98

1.04

0.392

1.02

0.99

1.06

0.176

1.02

1.00

1.05

0.069

Emotional function

1.00

0.94

1.05

0.912

0.99

0.96

1.03

0.730

1.00

0.95

1.06

0.997

1.05

1.01

1.09

0.022

Cognitive function

1.01

0.95

1.08

0.700

1.05

1.01

1.09

0.007

1.07

1.01

1.14

0.028

1.02

0.98

1.06

0.397

Social function

1.01

0.97

1.05

0.691

1.02

0.98

1.06

0.365

1.02

0.97

1.08

0.406

0.96

0.93

1.00

0.035

Nausea/vomiting

1.03

0.93

1.13

0.600

1.03

0.96

1.10

0.450

1.06

0.96

1.16

0.225

0.99

0.92

1.06

0.782

Pain

0.99

0.95

1.04

0.732

1.02

0.98

1.05

0.330

0.96

0.92

1.00

0.073

1.00

0.97

1.03

0.847

Dyspnoea

1.00

0.94

1.05

0.952

0.99

0.95

1.04

0.749

0.99

0.95

1.03

0.675

0.99

0.95

1.03

0.516

Insomnia

0.98

0.95

1.01

0.165

0.99

0.97

1.01

0.478

1.02

0.99

1.05

0.253

1.00

0.98

1.03

0.902

Appetite loss

0.99

0.96

1.03

0.741

1.01

0.98

1.04

0.526

1.04

0.99

1.09

0.100

1.00

0.97

1.04

0.826

Constipation

1.07

1.02

1.13

0.005

1.04

1.01

1.08

0.026

0.99

0.95

1.04

0.691

0.99

0.95

1.03

0.533

Diarrhoea

0.98

0.94

1.03

0.419

1.00

0.97

1.03

0.885

1.02

0.99

1.06

0.196

1.00

0.98

1.04

0.746

  1. Main findings are highlighted in bold text
  2. Three clusters identified: Low adherence cluster (low adherence to endurance training and/or low adherence to resistance training), Mixed adherence cluster (low-to-moderate adherence to endurance training and moderate-to-high adherence to resistance training) and High adherence cluster (individuals with high adherence (high adherence to endurance training and moderate-to-high adherence to resistance training)
  3. RRR, relative risk ratio; LCI, lower confidence interval; UCI, upper confidence interval; MFI, multidimensional fatigue inventory