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Table 1 Clusters of significant volume changes in contrast t3-t1, describing GM volume decrease from start to time point 3 at a mean of 4001 km

From: Regionally accentuated reversible brain grey matter reduction in ultra marathon runners detected by voxel-based morphometry

Functional region

Anatomical localisation

Side

Brodmann area

x

y

z

z-score

Bilateral temporal cortex and parietal lobe

Medial temporal gyrus

Right

21

51

-43

7

6.60

37

45

-62

2

6.35

22

54

-39

1

6.35

Superior temporal gyrus and postcentral gyrus, parietal lobe

Right

42, 40

56

-30

19

5.73

Medial temporal gyrus

Left

21

-56

-29

-7

5.59

21

-53

-37

-5

5.39

21

-48

-42

0

5.39

Uncus

Left

20

-34

-19

-28

5.69

Bilateral occipitoparietal cortex

Angular gyrus

Right

39

46

-51

33

6.07

Precuneus

Right

19

32

-68

34

5.47

Precuneus

Right

7

14

-68

41

5.51

7

8

-72

45

5.51

19

15

-81

38

5.42

Precuneus

 

19

-40

-71

38

5.96

Angular gyrus

Left

39

-48

-62

34

5.29

Precuneus

 

7

-24

-73

43

5.08

Precuneus

Left

7

-15

-75

48

5.20

Lingual gyrus

Left

18

-15

-85

-9

5.12

Bilateral ACC/perigenual cingulate cortex adjacent medial prefrontal cortex

Cingulate gyrus

Left

24

-3

4

26

6.15

Left

24

-7

1

34

5.96

Right

24

1

-3

31

5.68

Cingulate gyrus

Right

31

1

-27

35

5.16

Superior frontal gyrus

Left

8

-3

39

46

5.43

Superior frontal gyrus

Right

9

27

51

29

5.81

Medial frontal gyrus

Left

10, 11

-3

44

-11

5.13

Right caudate head

Caudate

 

Caudate head

13

12

0

5.50

Caudate

Right

Caudate head

6

7

3

5.42

Anterior cingulate

 

24

5

27

-4

5.36

  1. Masking as described in the method section, p < 0.05 FWE corrected. In the columns x, y and z brain coordinates in stereotactic MNI-space are listed. Z-score refers to the standard norm distribution’s z-statistic.