Low back pain and FokI (rs2228570) polymorphism of vitamin D receptor in athletes

Table 3 VDR-FokI genotypes and alleles in 60 athletes, and comparison between 24 athletes with LBP episodes and 36 athletes without LBP episodes

VDR-FokI genotype or allele	All athletes, N = 60, n (%)	LBP, N = 24, n (%)	No-LBP, N = 36, n (%)	Crude OR (CI)	Crude P value	Adjusted^a OR (CI)	Adjusted^a P value
FF genotype	24 (40.0)	14 (58.3)	10 (27.8)	3.64 (1.22–10.8)	0.018^b	5.78 (1.41–23.8)	0.015
Ff genotype	34 (56.7)	10 (41.7)	24 (66.7)	0.36 (0.12–1.04)	0.056^b	0.24 (0.06–0.93)	0.039
ff genotype	2 (3.3)	0 (−)	2 (5.6)	–^c	–^c	–^c	–^c
F allele	82/120 (68.3)	38/48 (79.2)	44/72 (61.1)	2.42 (1.04–5.61)	0.037^b	2.55 (1.02–6.43)	0.046
f allele	38/120 (31.7)	10/48 (20.8)	28/72 (38.9)	0.41 (0.18–0.96)	0.037^b	0.39 (0.16–0.98)	0.046

^aOR was adjusted by multivariate analysis for age, sex, BMI, ever smoking, exposure to vibrations, physical job demand, and weekly hours of physical exercise
^bP comparison of LBP and no-LBP by two-tailed Pearson’s chi squared test
^cOR not countable because one of the compared groups had zero subjects

ISSN: 2052-1847