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Table 3 VDR-FokI genotypes and alleles in 60 athletes, and comparison between 24 athletes with LBP episodes and 36 athletes without LBP episodes

From: Low back pain and FokI (rs2228570) polymorphism of vitamin D receptor in athletes

VDR-FokI genotype or allele All athletes, N = 60, n (%) LBP, N = 24, n (%) No-LBP, N = 36, n (%) Crude OR (CI) Crude P value Adjusteda OR (CI) Adjusteda P value
FF genotype 24 (40.0) 14 (58.3) 10 (27.8) 3.64 (1.22–10.8) 0.018b 5.78 (1.41–23.8) 0.015
Ff genotype 34 (56.7) 10 (41.7) 24 (66.7) 0.36 (0.12–1.04) 0.056b 0.24 (0.06–0.93) 0.039
ff genotype 2 (3.3) 0 (−) 2 (5.6) c c c c
F allele 82/120 (68.3) 38/48 (79.2) 44/72 (61.1) 2.42 (1.04–5.61) 0.037b 2.55 (1.02–6.43) 0.046
f allele 38/120 (31.7) 10/48 (20.8) 28/72 (38.9) 0.41 (0.18–0.96) 0.037b 0.39 (0.16–0.98) 0.046
  1. aOR was adjusted by multivariate analysis for age, sex, BMI, ever smoking, exposure to vibrations, physical job demand, and weekly hours of physical exercise
  2. bP comparison of LBP and no-LBP by two-tailed Pearson’s chi squared test
  3. cOR not countable because one of the compared groups had zero subjects