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Table 7 Joint of acute hormone responses to stimulation tests and resting levels after induction of NFOR/FOR state

From: Hormonal aspects of overtraining syndrome: a systematic review

Hormone Quantity of studies Normal response Blunted response Exacerbated response
Cortisol 26 (65.0%) 18 (69.2%) 8 (30.8%) -
Total T 18 (45.0%) 14 (77.8%) 3 (16.7%) 1 (5.9%)
GH 13 (32.5%) 7 (53.8%) 5 (38.4%) 1 (7.8%)
T/C 10 (25.0%) 5 (50.0%) 4 (40.0%) 1 (10.0%)
ACTH 10 (25.0%) 6 (60.0%) 4 (40.0%) -
Plasma catecholamines 9 (22.5%) 4 (44.4%) 4 (44.4%) 1 (11.1%)
Insulin 8 (20.0%) 6 (75.0%) 2 (25.0%) -
LH 8 (20.0%) 7 (87.5%) 1 (12.5%) -
Prolactin 6 (15.0%) 4 (66.7%) 2 (33.3%) -
FSH 6 (15.0%) 5 (83.3%) 1 (16.7%) -
IGF-1 5 (12.5%) 3 (60.0%) 1 (20.0%) 1 (20.0%)
Aldosterone 5 (12.5%) 1 (20.0%) 2 (40.0%) 2 (40.0%)
Free T 3 (7.5%) 1 (33.3%) 1 (33.3%) 1 (33.3%)
T4 2 (5.0%) 2 (100%) - -
T3 2 (5.0%) 2 (100%) - -
NUC 2 (5.0%) - 2 (100%) -
Salivary C 2 (5.0%) - 2 (100%) -
Salivary T 2 (5.0%) 1 (50.0%) 1 (50.0%) -
NUC 2 (5.0%) 1 (50.0%) 1 (50.0%) -
IGFBP-3 2 (5.0%) 1 (50.0%) 1 (50.0%) -
IGF-1/IGFBP-3 2 (5.0%) 2 (100%) - -
SHBG 1 1 - -
DHEA-S 1 1 - -
Peptide F 1 1 - -
Fertility 1 - 1 -
Beta-2 muscle receptors 1 - 1 -
  1. NUC Nocturnal urinary catecholamines, T/C testosterone/cortisol ratio, T/SHBG testosterone/sex hormone binding globulin, T3 thyronine, T4 thyroxine, salivary C salivary cortisol, salivary T salivary testosterone, IGF-1/IGFBP-3 IGF-1/IGFBP3 ratio, fertility evaluation by semen analysis