Table 1 Indication of physiological variables measured and timepoints of each measurement
Variable | Timepoints measured |
|---|---|
Primary outcome | |
 Peak VO2, HR at peak VO2, HR at 65 and 85% peak VO2 | Baseline, post-intervention |
Secondary outcomes | |
 Anthropometry | |
  Skinfolds | Baseline, post-intervention |
  Body mass and waist:hip | Baseline, every 4 weeks during intervention, post-intervention |
 Brachial blood pressure | Baseline, post-intervention |
 Central blood pressure and arterial stiffness | Baseline, post-intervention |
 Echocardiography | Baseline, post-intervention |
 Biomarkers of metabolic and cardiovascular health | Baseline, post-intervention |
 Feasibility (adherence and dropout rate) | Baseline, every 4 weeks during intervention, post-intervention |
 Accelerometry | Baseline, every 4 weeks during intervention, post-intervention |