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Table 2 Percentage changes from baseline of the upper extremity muscle strength on the dominant limb are presented as mean (SD) at posttest (POST) in each group

From: Non-linear dose response effect of cathodal transcranial direct current stimulation on muscle strength in young healthy adults: a randomized controlled study

Muscles of the dominant limb

Groups

Percentage change from baseline

Within group comparison

Between group comparison

POST [Mean (SD)]

Z

p value

Effect size

Overall

Post hoc

Comparison groups

p value

Elbow flexor

Sham tDCS

− 0.36 (3.04)

− 1.334

0.204

0.39

0.002**

Sham versus 1 mA

0.013*

 

1.0 mA ctDCS

− 9.94 (7.27)

− 3.059

< 0.001***

0.88

 

Sham versus 1.5 mA

0.034*

 

1.5 mA ctDCS

− 9.42 (7.11)

− 3.059

< 0.001***

0.88

 

Sham versus 2 mA

0.972

 

2.0 mA ctDCS

0.15 (10.52)

0.392

0.733

0.11

 

1 mA versus 1.5 mA

0.989

       

1 mA versus 2 mA

0.047*

       

1.5 mA versus 2 mA

0.104

Elbow extensor

Sham tDCS

1.21 (3.55)

0.471

0.677

0.14

< 0.001***

Sham versus 1 mA

0.037*

 

1.0 mA ctDCS

− 10.17 (10.56)

− 2.432

0.012*

0.70

 

Sham versus 1.5 mA

0.009**

 

1.5 mA ctDCS

− 10.75 (5.44)

− 3.059

< 0.001***

0.88

 

Sham versus 2 mA

0.996

 

2.0 mA ctDCS

2.96 (7.59)

0.706

0.519

0.20

 

1 mA versus 1.5 mA

0.966

       

1 mA versus 2 mA

0.019*

       

1.5 mA versus 2 mA

0.004**

Wrist extensor

Sham tDCS

0.62 (5.14)

− 0.471

0.677

0.14

< 0.001***

Sham versus 1 mA

0.006**

 

1.0 mA ctDCS

− 11.49 (8.03)

− 3.059

< 0.001***

0.88

 

Sham versus 1.5 mA

0.048*

 

1.5 mA ctDCS

− 8.79 (9.44)

− 2.432

0.012*

0.70

 

Sham versus 2 mA

0.999

 

2.0 mA ctDCS

− 0.92 (7.01)

− 0.196

0.850

0.06

 

1 mA versus 1.5 mA

0.897

       

1 mA versus 2 mA

0.010*

       

1.5 mA versus 2 mA

0.072

  1. *Indicated p < 0.05, ** indicated p < 0.01, and *** indicated p < 0.001