Table 1 Echocardiographic data at baseline and 7 days after doxorubicin treatment

HR, beats/min

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

606 ± 86

643 ± 33

597 ± 34

586 ± 78

595 ± 43

581 ± 34^*

607 ± 49

598 ± 54

SED (n = 6)

N-C (n = 10) C (n = 12)

606 ± 86

614 ± 41

602 ± 69

595 ± 43

570 ± 29^{* †}

617 ± 47^†

SWT, mm

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

0.767 ± 0.082

0.743 ± 0.053

0.800 ± 0.058

0.750 ± 0.053

0.717 ± 0.041

0.757 ± 0.079

0.700 ± 0.058^**

0.687 ± 0.035^*

SED (n = 6)

N-C (n = 10) C (n = 12)

0.767 ± 0.082

0.760 ± 0.052

0.767 ± 0.065

0.717 ± 0.041

0.710 ± 0.088

0.717 ± 0.039

PWT, mm

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

0.750 ± 0.084

0.743 ± 0.053

0.743 ± 0.053

0.763 ± 0.106

0.717 ± 0.075

0.729 ± 0.095

0.657 ± 0.079

0.687 ± 0.064

SED (n = 6)

N-C (n = 10) C (n = 12)

0.750 ± 0.084

0.770 ± 0.067

0.733 ± 0.078

0.717 ± 0.075

0.700 ± 0.082

0.683 ± 0.083

LVDd, mm

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

3.233 ± 0.413

3.257 ± 0.282

3.271 ± 0.386

3.200 ± 0.214

3.183 ± 0.172

3.186 ± 0.261

3.143 ± 0.190

3.163 ± 0.233

SED (n = 6)

N-C (n = 10) C (n = 12)

3.233 ± 0.413

3.210 ± 0.288

3.267 ± 0.293

3.183 ± 0.172

3.180 ± 0.225

3.150 ± 0.224

LVDs, mm

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

1.550 ± 0.217

1.500 ± 0.258

1.557 ± 0.299

1.550 ± 0.160

1.717 ± 0.293

1.643 ± 0.282

1.643 ± 0.172

1.625 ± 0.103

SED (n = 6)

N-C (n = 10) C (n = 12)

1.550 ± 0.217

1.480 ± 0.230

1.583 ± 0.233

1.717 ± 0.293

1.710 ± 0.218^**

1.575 ± 0.136

LVFS, %

SED (n = 6)

G1 (n = 7)

G2 (n = 7)

G3 (n = 8)

52 ± 3

53 ± 6

53 ± 5

51 ± 3

46 ± 7^**

49 ± 5^*

48 ± 4^*

50 ± 4

SED (n = 6)

N-C (n = 10) C (n = 12)

52 ± 3

54 ± 5

51 ± 4

46 ± 7^**

47 ± 5^**

50 ± 3