Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

Table 2 Variables associated with VO_2peak (mL/kg/min) assessed by multiple linear regression

Variable	Full model^a, R² = 0.68 Regression coefficients	95% CI	p-value	Final model^b, R² = 0.66 Regression coefficients	95% CI	p-value
Age, years	− 0.16	(− 0.31; − 0.01)	0.04	− 0.18	(− 0.31; − 0.04)	0.01
Female gender	− 1.56	(− 5.09; 1.97)	0.38	− 0.53	(− 3.09; 2.03)	0.68
Cigarettes/snuff, yes	0.24	(− 2.71; 3.19)	0.87
Fatmass, % of body weight^	− 0.66	(− 0.88; − 0.43)	< 0.001	− 0.67	(− 0.85; − 0.48)	< 0.001
Systolic blood pressure, mmHg	0.04	(− 0.05; 0.13)	0.38
HDL-c, mmol L⁻¹	1.27	(− 1.89; 4.43)	0.42
Physical activity index (0–45 points, 45 = best)	0.13	(− 0.01; 0.27)	0.08	0.13	(0.00; 0.27)	0.05
Disease activity category (1–4, 1 = remission)	− 0.49	(− 1.78; 0.79)	0.45
NRS fatigue (0–10, 0 = best)	0.39	(− 0.19; 0.96)	0.18
Cons	49.2			57.37

^single missing data imputed by simple mean imputation
^aFull model including age, gender, use of cigarettes/snuff, fatmass (% bodyweight), systolic blood pressure, HDL-c, physical activity index and NRS fatigue as independent variables
^bFinal model including age, gender, fatmass (% bodyweight) and physical activity index as independent variables
HDL-c High-density lipoprotein cholesterol, NRS Numerical Rating Scale

ISSN: 2052-1847